Glycogen Synthase anticorps (pSer641)

N° du produit ABIN303100

Cet anticorps Lapin Polyclonal détecte spécifiquement Glycogen Synthase dans WB, IP, EIA et IHC (p). Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour Glycogen Synthase anticorps (pSer641) (ABIN303100)

Antigène: Glycogen Synthase (GYS)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glycogen Synthase est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Glycogen Synthase anticorps

Épitope: pSer641

Specificité: This antibody is specific for the phosphorylated form of GS at S640. Phosphorylation of GS at S640 has been associated with Antiphospholipid Antibody Syndrome.

Purification: Immunoaffinity Chromatography.

Immunogène: Human Muscle Glycogen Synthase phospho peptide corresponding to a region of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH).

Information d'application

Indications d'application: Immunohistochemistry on Paraffin Sections (5 μg/mL). Western Blot. Immunoprecipitation. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01 % (w/v) Sodium Azide as preserevative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur Glycogen Synthase

Antigène: Glycogen Synthase (GYS)

Autre désignation: Glycogen Synthase

Sujet: Human muscle glycogen synthase (GS) is responsible for the biosynthesis of glycogen from phosphorylated glucose units. Mammalian liver and muscle contain GS consisting of four subunits with a total molecular weight of 360,000. GS is subject to regulation through both allosteric and covalent modification and occurs in two forms: the phosphorylated inactive form, and the dephos-phorylated active form. GS is inactivated by the serine/threonine kinase called glycogen synthase kinase-3b that mainly functions to phos-phorylate muscle glycogen synthase.Synonyms: GYS, GYS1, muscle Glycogen Synthase

ID gène: 2997

NCBI Accession: NP_001155059

UniProt: P13807